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Course info
KCH / BIO1
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Course description
Department/Unit / Abbreviation
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KCH
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BIO1
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Academic Year
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2023/2024
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Academic Year
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2023/2024
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Title
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Biochemistry 1
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Form of course completion
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Exam
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Form of course completion
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Exam
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Accredited / Credits
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Yes,
3
Cred.
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Type of completion
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Combined
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Type of completion
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Combined
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Time requirements
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Lecture
3
[Hours/Week]
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Course credit prior to examination
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No
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Course credit prior to examination
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No
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Automatic acceptance of credit before examination
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Yes in the case of a previous evaluation 4 nebo nic.
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Included in study average
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YES
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Language of instruction
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Czech
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Occ/max
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Automatic acceptance of credit before examination
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Yes in the case of a previous evaluation 4 nebo nic.
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Summer semester
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23 / -
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0 / -
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0 / -
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Included in study average
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YES
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Winter semester
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0 / -
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0 / -
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0 / -
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Repeated registration
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NO
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Repeated registration
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NO
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Timetable
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Yes
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Semester taught
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Summer semester
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Semester taught
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Summer semester
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Minimum (B + C) students
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10
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Optional course |
Yes
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Optional course
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Yes
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Language of instruction
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Czech
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Internship duration
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0
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No. of hours of on-premise lessons |
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Evaluation scale |
1|2|3|4 |
Periodicity |
každý rok
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Periodicita upřesnění |
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Fundamental theoretical course |
No
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Fundamental course |
Yes
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Fundamental theoretical course |
No
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Evaluation scale |
1|2|3|4 |
Substituted course
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None
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Preclusive courses
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N/A
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Prerequisite courses
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N/A
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Informally recommended courses
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KCH/OCH
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Courses depending on this Course
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N/A
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Histogram of students' grades over the years:
Graphic PNG
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XLS
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Course objectives:
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The aim of this course is to acquire the fundamentals of descriptive biochemistry and to understand the autonomous and coupled metabolic processes associated with the exchange of substances with the energy profit and subject to regulation influence.
To understand the molecular interpretation of the mechanisms of important biochemical processes.
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Requirements on student
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To demonstrate the knowledge to the extent of lectures by the exam.
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Content
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1st Definition of the living organism, types of biomolecules and chemical bonds in living organisms.
Saccharides - sorting, functions in organisms, glycoside bonds, glycoproteins.
2nd Fatty acids, triglycerides, phospholipids etc., compound lipids, steroids, lipoproteins, biological functions.
3rd Amino acids, peptides, proteins, chemical properties, biological function, occurrence, primary, secondary and tertiary structure of proteins, biomembranes.
4th Basic kinetic parameters of biochemical processes, makroergic compounds. Enzymes - the composition, functions, sorting, kinetics of enzym reactions, regulation of enzyme activity.
Coenzymes and cofactors of enzymes, structure and function.
5th Anaerobic glycolysis, pentos cycle - the biological importance, its basic integrades, the energetic effect, oxidative decarboxylation of a-oxoacids.
6th Citric acid cycle - the course, the context of other metabolic pathways, energetic effect, glyoxylate cycle - the course, biological significance, milk glycolysis, alcohol fermentation.
7th Saccharides digestion, D-fructose and D-galactose metabolism.
Respiratory chain - the main level, biological significance, oxidative phosphorylation, chemiosmotic theory, glukoneogenesis.
8th Digestion of lipids, beta-oxidation of fatty acids, the synthesis of fatty acids. Digestion of proteins.
Non-transamination conversion of amino acids, transamination - the course, biological significance, examples. Decarboxylation of amino acids. Coded amino acid metabolism.
Purine and pyrimidine bases, synthesis and biodegradation, the structures of DNA and RNA.
9th Biosynthesis of DNA and RNA, DNA and RNA catabolism.
Genetic code, mutation.
Detoxification of ammonia, urea cycle.
Protein synthesis - the main stages of the process, viruses, principle of pathological effect.
10th Heme synthesis, degradation of hemoglobin, transport of oxygen and carbon dioxide through the blood, blood buffering system.
Photosynthesis - dark phase and the Calvin cycle.
11th Vitamins A, carotenoids, D, E, K and C - structure, biological function.
Hormones - basic distribution.
12th Regulation principles of biochemical processes, active and passive transport through membranes, mechanism, examples.
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Activities
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Fields of study
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Všechny důležité informace a materiály k předmětu jsou studentům k dispozici v Coursewaru.
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Guarantors and lecturers
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Literature
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Recommended:
Škárka B., Ferenčík M. Biochémia. Bratislava, Praha, Alfa/SNTL, 1983.
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Recommended:
Koštíř J. Biochemie. Avicenum Praha, 1974.
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Recommended:
Vodrážka, Zdeněk. Biochemie. Praha : Academia, 1996. ISBN 80-200-0600-1.
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Recommended:
Heřmánek, Miloslav. Biochemie : Celost. vysokošk. učebnice pro stud. pedag. a přírodovědeckých fakult. 1. vyd. Praha : Státní pedagogické nakladatelství, 1992. ISBN 80-04-21736-2.
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Recommended:
KODÍČEK M., VALENTOVÁ O., HYNEK R. Biochemie - chemický pohled na biologický svět. VŠCHT, Praha, 2018. ISBN 978-80-7592-013-3.
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Recommended:
SOFROVÁ, D. a kol. Biochemie - základní kurz. Karolinum. Praha, 2009. ISBN 978-80-2461-678-0.
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Recommended:
Vodrážka, Zdeněk. Biochemie, díl 2.
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Recommended:
Musil, Jan. Biochemie v obrazech a schématech. 1. vyd. Praha : Avicenum, 1976.
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Recommended:
Karlson, Peter. Základy biochemie. Praha : Academia, 1981.
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Recommended:
Doubrava, Jaroslav; Koštíř, Jiří; Kubík, Josef. Základy biochemie : Stud. příručka pro posl. fakult připravujících učitele. 1. vyd. Praha : SPN, 1984.
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On-line library catalogues
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Time requirements
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All forms of study
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Activities
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Time requirements for activity [h]
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Contact hours
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39
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Preparation for an examination (30-60)
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50
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Total
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89
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Prerequisites
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Knowledge - students are expected to possess the following knowledge before the course commences to finish it successfully: |
orientated in the system of chemical disciplines taught in high school |
to classify reactions from the physico-chemical point of view |
to divide the system of organic compounds |
to understand biochemical processes at the secondary level |
Skills - students are expected to possess the following skills before the course commences to finish it successfully: |
search for information in magazine and electronic resources |
to transform generally acquired knowledge into specific situations |
to work with basic biochemical literature |
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Learning outcomes
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Knowledge - knowledge resulting from the course: |
Specify biochemistry descriptive, functional and organizational (give examples) |
describe the course of biochemical processes |
Skills - skills resulting from the course: |
explain the course and importance of biochemical processes |
to break down the biochemical reactions from the energy point of view to the advantageous and disadvantageous |
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Assessment methods
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Knowledge - knowledge achieved by taking this course are verified by the following means: |
Combined exam |
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Teaching methods
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Knowledge - the following training methods are used to achieve the required knowledge: |
Lecture |
Self-study of literature |
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