|
|
Main menu for Browse IS/STAG
Course info
CBG / 9MOBB
:
Course description
Department/Unit / Abbreviation
|
CBG
/
9MOBB
|
Academic Year
|
2023/2024
|
Academic Year
|
2023/2024
|
Title
|
Molecular and cell biology
|
Form of course completion
|
Exam
|
Form of course completion
|
Exam
|
Accredited / Credits
|
No,
0
Cred.
|
Type of completion
|
Combined
|
Type of completion
|
Combined
|
Time requirements
|
Lecture
8
[Hours/Semester]
|
Course credit prior to examination
|
Yes
|
Course credit prior to examination
|
Yes
|
Automatic acceptance of credit before examination
|
Yes in the case of a previous evaluation 4 nebo nic.
|
Included in study average
|
YES
|
Language of instruction
|
-
|
Occ/max
|
|
|
|
Automatic acceptance of credit before examination
|
Yes in the case of a previous evaluation 4 nebo nic.
|
Summer semester
|
0 / -
|
0 / -
|
0 / -
|
Included in study average
|
YES
|
Winter semester
|
2 / -
|
0 / -
|
0 / -
|
Repeated registration
|
NO
|
Repeated registration
|
NO
|
Timetable
|
Yes
|
Semester taught
|
Winter semester
|
Semester taught
|
Winter semester
|
Minimum (B + C) students
|
10
|
Optional course |
Yes
|
Optional course
|
Yes
|
Language of instruction
|
-
|
Internship duration
|
0
|
No. of hours of on-premise lessons |
|
Evaluation scale |
1|2|3|4 |
Periodicity |
každý rok
|
Evaluation scale for credit before examination |
S|N |
Periodicita upřesnění |
|
Fundamental theoretical course |
No
|
Fundamental course |
No
|
Fundamental theoretical course |
No
|
Evaluation scale |
1|2|3|4 |
Evaluation scale for credit before examination |
S|N |
Substituted course
|
CBG/MOBB
|
Preclusive courses
|
N/A
|
Prerequisite courses
|
N/A
|
Informally recommended courses
|
N/A
|
Courses depending on this Course
|
N/A
|
Histogram of students' grades over the years:
Graphic PNG
,
XLS
|
Course objectives:
|
This course is aimed to repeat basic knowledge of cell and its chemical composition, prokaryotic and eukaryotic cell, genome (prokaryotic and eukaryotic) and its structure, chromosomes and their structure.
|
Requirements on student
|
Fulfilment terms for to grant credit. Knowledge of lectured topics.
|
Content
|
1. Cell cycle and its regulation, apoptosis, necrosis.
2. Reproduction of cells, mitosis and meiosis at the molecular level, consequences of these processes in carcinogenesis and reproduction process.
3. Process of carcinogenesis, molecular genetic methods and their application in pathology. Laser microdissection, Real Time PCR, chip technology.
4. Gene imprinting, its significance, examples of human genetics, methods of study.
5. Characterization of viruses, methods of their detection and characterization.
6. Differentiation and development of multicellular organism, problem of homeobox genes.
7. Immune system molecules, their function and importance in immune responses, conditionality of their diversity.
8. Methodological basics of biotechnology, cloning, vectors, restriction enzymes and their significance, methods of gene expression monitoring, transgenic animals.
9. Cloning of animals.
10. Gene therapy and possibilities of tissue engineering, pharmacogenetics.
11. Identification of persons, microchimerism, problems of free circulating nucleic acids.
12. Overview of methods studied - summary (methods of molecular genetics: PCR and its modification, sequencing, methods of gene expression analysis
13. cloning, overview of microscopic techniques, immunohistochemistry, in situ hybridization, event. visit a specialized laboratory.
|
Activities
|
|
Fields of study
|
|
Guarantors and lecturers
|
|
Literature
|
-
Basic:
Alberts, B. a kol. Základy buněčné biologie : úvod do molekulární biologie buňky. Ústí nad Labem: Espero Publishing, 1998. ISBN 80-902906-2-0.
-
Recommended:
De Duve, Ch. A Guided Tour of the Living Cell. University Press, 1985.
-
Recommended:
Vodrážka, Zdeněk. Biochemie. Praha : Academia, 1996. ISBN 80-200-0600-1.
-
Recommended:
Kubišta, V. Buněčné základy životních dějů. Praha, 1998.
-
Recommended:
Vonka, Z. a kol. Kapitoly molekulové biologie. H&H Praha, 1992.
-
Recommended:
Šmarda J. Metody molekulární biologie. Masarykova univerzita, 2010. ISBN 9788021038417.
-
Recommended:
Bresler, Semen Jefimovič. Molekulární biologie. Praha : Academia, 1979.
-
Recommended:
Vlasák. Molekulární biologie.. Biologická fakulta JCU, 1998.
-
Recommended:
Žurovec, J. Molekulární biologie živočichů. Biologická fakulta JCU, 1999.
-
Recommended:
Rosypal, S. a kol. Nový přehled biologie. Praha, 2003.
-
Recommended:
Kubišta, V. Obecná biologie. Fortuna Praha, 2000.
-
Recommended:
Rosypal, Stanislav. Přehled biologie. Praha : Scientia, 1994. ISBN 80-85827-32-8.
-
Recommended:
Rosypal, Stanislav. Úvod do molekulární biologie. 2.,rozš. vyd. Brno : Stanislav Rosypal, 1997.
-
Recommended:
Karlson, Peter. Základy biochemie. Praha : Academia, 1981.
-
On-line library catalogues
|
Time requirements
|
All forms of study
|
Activities
|
Time requirements for activity [h]
|
Preparation for an examination (30-60)
|
30
|
Contact hours
|
26
|
Total
|
56
|
|
Prerequisites
|
Knowledge - students are expected to possess the following knowledge before the course commences to finish it successfully: |
to know the basic study of molecular and cell biology at the level of bachelor study of biology
to know the basics of replication, transcription, translation and their regulation
Know the types of distribution and cause of mutations
to know the basics of DNA transposition
to know the basic methods of molecular biology
to know the basic science of genetics at the level of bachelor study of biology |
Skills - students are expected to possess the following skills before the course commences to finish it successfully: |
use the knowledge of a bachelor's degree program, or supplement the curriculum at this level
analytically linking facts into a meaningful whole |
Competences - students are expected to possess the following competences before the course commences to finish it successfully: |
N/A |
N/A |
|
Learning outcomes
|
Knowledge - knowledge resulting from the course: |
Know the chemical composition of the cell, biopolymers, chaperons, genomics . |
To know the genome and its structure. |
To know the methods of studying genomes . |
To know repetitive sequences and transposons. |
To know the cytoskeletal principle of the cell organization, the components of the cytoskeleton and their function. |
Know intercellular signaling, hormones and receptors. |
Skills - skills resulting from the course: |
Describe the construction of prokaryotic and eukaryotic cells. |
Use terminology of molecular biology. |
Competences - competences resulting from the course: |
N/A |
|
Assessment methods
|
Knowledge - knowledge achieved by taking this course are verified by the following means: |
Written exam |
Skills - skills achieved by taking this course are verified by the following means: |
Written exam |
|
Teaching methods
|
Knowledge - the following training methods are used to achieve the required knowledge: |
Lecture with visual aids |
Skills - the following training methods are used to achieve the required skills: |
Lecture |
Competences - the following training methods are used to achieve the required competences: |
Lecture |
|
|
|
|